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Endothelin enhances the contractile responsiveness of adult rat ventricular myocytes to calcium by a pertussis toxin-sensitive pathway.

It has long been assumed that the primary influences regulating cardiac contractility are the extent of mechanical loading of muscle fibers and the activity of the autonomic nervous system. However, the vasoactive peptide endothelin, initially found in vascular endothelium, is among the most potent...

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Autori principali: Kelly, R A, Eid, H, Krämer, B K, O'Neill, M, Liang, B T, Reers, M, Smith, T W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC296846/
https://ncbi.nlm.nih.gov/pubmed/2120283
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