Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells.

To determine whether insulin secretion is affected by a blockage of gap junctions between B cells, we have studied the secretion of rat pancreatic islets of Langerhans, primary dispersed islet cells, and cells of the RINm5F line, during short-term exposure to heptanol. Within minutes, this alkanol b...

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Pubblicato in:	J Clin Invest
Autori principali:	Meda, P, Bosco, D, Chanson, M, Giordano, E, Vallar, L, Wollheim, C, Orci, L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296790/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1697604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114772
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