Peroxynitrite Mediates Diabetes-Induced Endothelial Dysfunction: Possible Role of Rho Kinase Activation

Endothelial dysfunction is characterized by reduced bioavailability of NO due to its inactivation to form peroxynitrite or reduced expression of eNOS. Here, we examine the causal role of peroxynitrite in mediating diabetes-induced endothelial dysfunction. Diabetes was induced by STZ-injection, and r...

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Hlavní autoři: El-Remessy, Azza B., Tawfik, Huda E., Matragoon, Suraporn, Pillai, Bindu, Caldwell, Ruth B., Caldwell, R. William
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967829/
https://ncbi.nlm.nih.gov/pubmed/21052489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/247861
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