Peroxynitrite Mediates Diabetes-Induced Endothelial Dysfunction: Possible Role of Rho Kinase Activation

Endothelial dysfunction is characterized by reduced bioavailability of NO due to its inactivation to form peroxynitrite or reduced expression of eNOS. Here, we examine the causal role of peroxynitrite in mediating diabetes-induced endothelial dysfunction. Diabetes was induced by STZ-injection, and r...

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Bibliographic Details
Main Authors: El-Remessy, Azza B., Tawfik, Huda E., Matragoon, Suraporn, Pillai, Bindu, Caldwell, Ruth B., Caldwell, R. William
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967829/
https://ncbi.nlm.nih.gov/pubmed/21052489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/247861
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