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An integrative method for scoring candidate genes from association studies: application to warfarin dosing

BACKGROUND: A key challenge in pharmacogenomics is the identification of genes whose variants contribute to drug response phenotypes, which can include severe adverse effects. Pharmacogenomics GWAS attempt to elucidate genotypes predictive of drug response. However, the size of these studies has sev...

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Main Authors: Tatonetti, Nicholas P, Dudley, Joel T, Sagreiya, Hersh, Butte, Atul J, Altman, Russ B
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967750/
https://ncbi.nlm.nih.gov/pubmed/21044367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S9-S9
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