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An integrative method for scoring candidate genes from association studies: application to warfarin dosing

BACKGROUND: A key challenge in pharmacogenomics is the identification of genes whose variants contribute to drug response phenotypes, which can include severe adverse effects. Pharmacogenomics GWAS attempt to elucidate genotypes predictive of drug response. However, the size of these studies has sev...

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Hauptverfasser: Tatonetti, Nicholas P, Dudley, Joel T, Sagreiya, Hersh, Butte, Atul J, Altman, Russ B
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967750/
https://ncbi.nlm.nih.gov/pubmed/21044367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S9-S9
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