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Quantitative dynamic footprinting microscopy reveals mechanisms of neutrophil rolling
We introduce quantitative dynamic footprinting microscopy to resolve neutrophil rolling on P-selectin. We show that the footprint of a rolling neutrophil is four times larger than previously thought, the P-selectin-PSGL-1 bonds are relaxed at the leading edge of the rolling cell, compressed under th...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967732/ https://ncbi.nlm.nih.gov/pubmed/20871617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1508 |
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