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Mast cell chymase potentiates histamine-induced wheal formation in the skin of ragweed-allergic dogs.

Skin mast cells release the neutral protease chymase along with histamine during degranulation. To test the hypothesis that chymase modulates histamine-induced plasma extravasation, we measured wheal formation following intradermal injection of purified mast cell chymase and histamine into the skin...

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Dettagli Bibliografici
Autori principali: Rubinstein, I, Nadel, J A, Graf, P D, Caughey, G H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC296760/
https://ncbi.nlm.nih.gov/pubmed/2384602
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