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Inhibition of human colony-forming-unit erythroid by tumor necrosis factor requires accessory cells.

Recombinant tumor necrosis factor (rTNF) inhibits erythropoiesis in vivo and in vitro. To study the mechanism of this inhibition, the effect of rTNF on highly purified human CFU-erythroid (E) (mean purity 63.5%), which were generated from peripheral blood burst-forming units-erythroid (BFU-E), was c...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Means, R T, Dessypris, E N, Krantz, S B
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296757/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2384599/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114741
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