A protein-centric approach for the identification of folate enzymes from the malarial parasite, Plasmodium falciparum, using OFFGEL™ solution-based isoelectric focussing and mass spectrometry

BACKGROUND: Plasmodium species are difficult to study using proteomic technology because they contain large amounts of haemoglobin-derived products (HDP), generated by parasite breakdown of host haemoglobin. HDP are known to interfere with isoelectric focussing, a cornerstone of fractionation strate...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: O'Cualain, Ronan DM, Hyde, John E, Sims, Paul FG
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Methodology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967559/
https://ncbi.nlm.nih.gov/pubmed/20955557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-286
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