Chemokine gene expression in lung CD8 T cells correlates with protective immunity in mice immunized intra-nasally with Adenovirus-85A

BACKGROUND: Immunization of BALB/c mice with a recombinant adenovirus expressing Mycobacterium tuberculosis (M. tuberculosis) antigen 85A (Ad85A) protects against aerosol challenge with M. tuberculosis only when it is administered intra-nasally (i.n.). Immunization with Ad85A induces a lung-resident...

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Hlavní autoři: Lee, Lian N, Baban, Dilair, Ronan, Edward O, Ragoussis, Jiannis, Beverley, Peter CL, Tchilian, Elma Z
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967494/
https://ncbi.nlm.nih.gov/pubmed/20942964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-3-46
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