Circulating Myeloid Dendritic Cells of Advanced Cancer Patients Result in Reduced Activation and a Biased Cytokine Profile in Invariant NKT Cells

CD1d-restricted invariant NKT (iNKT) cells play important regulatory roles in various immune responses, including antitumor immune responses. Previous studies have demonstrated quantitative and qualitative defects in iNKT cells of cancer patients, and these defects are clinically relevant as they ar...

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Auteurs principaux: van der Vliet, Hans J. J., Wang, Ruojie, Yue, Simon C., Koon, Henry B., Balk, Steven P., Exley, Mark A.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967461/
https://ncbi.nlm.nih.gov/pubmed/18490728
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