Generation of Antitumor Invariant NKT Cell Lines in Multiple Myeloma and Promotion of Their Functions via Lenalidomide: A Strategy for Immunotherapy

PURPOSE: CD1d-restricted invariant NKT (iNKT) cells are important immunoregulatory cells in antitumor immune responses. However, the quantitative and qualitative defects of iNKT cells in advanced multiple myeloma (MM) hampered their antitumor effects. Therefore, the development of functional iNKT ce...

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Autors principals: Song, Weihua, van der Vliet, Hans J. J., Tai, Yu-Tzu, Prabhala, Rao, Wang, Ruojie, Podar, Klaus, Catley, Laurence, Shammas, Masood, Anderson, Kenneth C., Balk, Steven P., Exley, Mark A., Munshi, Nikhil C.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967459/
https://ncbi.nlm.nih.gov/pubmed/18980990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-5290
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