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Cnr interferes with dimerization of the replication protein α in phage-plasmid P4

DNA replication of phage-plasmid P4 in its host Escherichia coli depends on its replication protein α. In the plasmid state, P4 copy number is controlled by the regulator protein Cnr (copy number regulation). Mutations in α (α(cr)) that prevent regulation by Cnr cause P4 over-replication and cell de...

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Udgivet i:Nucleic Acids Res
Principais autores: Tocchetti, Arianna, Serina, Stefania, Oliva, Ilaria, Dehò, Gianni, Ghisotti, Daniela
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11139624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.2.536
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