Sequential phase II Southwest Oncology Group studies (S0012 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with cyclosporine, in older patients with previously untreated acute myeloid leukemia (AML)

PURPOSE: Attempts to overcome multi-drug resistance (MDR) have been limited by toxicities. To investigate the effect of reducing peak drug levels, we performed sequential studies using continuous infusion daunorubicin and cytarabine without (AD) and then with cyclosporine (ADC) in older patients wit...

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Detalhes bibliográficos
Main Authors: Chauncey, Thomas R., Gundacker, Holly, Shadman, Mazyar, List, Alan F., Dakhil, Shaker R., Erba, Harry P., Slovak, Marilyn L., Chen, I-Ming, Willman, Cheryl L., Kopecky, Kenneth J., Appelbaum, Frederick R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967366/
https://ncbi.nlm.nih.gov/pubmed/19821823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2009.07919.x
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