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Quantitative understanding of cell signaling: The importance of membrane organization

Systems biology modeling of signal transduction pathways traditionally employs ordinary differential equations, deterministic models based on assumptions of spatial homogeneity. However, this can be a poor approximation for certain aspects of signal transduction, especially its initial steps: the ce...

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Detalhes bibliográficos
Main Authors: Radhakrishnan, Krishnan, Halász, Ádám, Vlachos, Dion, Edwards, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967365/
https://ncbi.nlm.nih.gov/pubmed/20829029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2010.08.006
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