Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium.

Autocrine stimulation of the epidermal growth factor receptor (EGF-R), by coexpression of transforming growth factor-alpha (TGF-alpha), causes malignant transformation of some fibroblast cell lines. TGF-alpha and EGF-R are both known to be expressed in colon carcinoma tissue and have been shown coex...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Markowitz, S D, Molkentin, K, Gerbic, C, Jackson, J, Stellato, T, Willson, J K
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296730/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2365825/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114709
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