Failure of low-dose recombinant human IL-2 to support the survival of virus-specific CTL clones infused into severe combined immunodeficient foals: lack of correlation between in vitro activity and in vivo efficacy

Although CTL are important for control of lentiviruses, including equine infectious anemia virus (EIAV), it is not known if CTL can limit lentiviral replication in the absence of CD4 help and neutralizing antibody. Adoptive transfer of EIAV-specific CTL clones into severe combined immunodeficient (S...

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Main Authors: Mealey, Robert H., Littke, Matt H., Leib, Steven R., Davis, William C., McGuire, Travis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967287/
https://ncbi.nlm.nih.gov/pubmed/17727961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vetimm.2007.07.011
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