MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)(8)-dendron for targeting

The synthesis of a polylysine dendron containing eight GdDOTA units conjugated to peptoid dimer known to have a high affinity for the vascular endothelial growth factor receptor 2 (VEGFR2) is described. This simple low molecular weight system with a molecular r(1) relaxivity of ~48 mM(−1)s(−1) is sh...

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Hlavní autoři: De León-Rodríguez, Luis M., Lubag, Angelo, Udugamasooriya, D. Gomika, Proneth, Bettina, Brekken, Rolf A., Sun, Xiankai, Kodadek, Thomas, Sherry, A. Dean
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967214/
https://ncbi.nlm.nih.gov/pubmed/20795620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja105563a
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