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MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)(8)-dendron for targeting
The synthesis of a polylysine dendron containing eight GdDOTA units conjugated to peptoid dimer known to have a high affinity for the vascular endothelial growth factor receptor 2 (VEGFR2) is described. This simple low molecular weight system with a molecular r(1) relaxivity of ~48 mM(−1)s(−1) is sh...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967214/ https://ncbi.nlm.nih.gov/pubmed/20795620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja105563a |
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