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Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance.

The nucleotide sequence was determined for all 22 exons of the insulin receptor gene from three patients with genetic syndromes associated with extreme insulin resistance. In all three patients, insulin resistance was caused by decreased insulin binding to the cell surface. The patient with leprecha...

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Detaylı Bibliyografya
Asıl Yazarlar: Kadowaki, T, Kadowaki, H, Rechler, M M, Serrano-Rios, M, Roth, J, Gorden, P, Taylor, S I
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1990
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC296715/
https://ncbi.nlm.nih.gov/pubmed/2365819
Etiketler: Etiketle
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