Urokinase has direct catalytic activity against fibrinogen and renders it less clottable by thrombin.

Recently, we demonstrated that tissue plasminogen activator directly releases fibrinopeptides A and B (FPA and FPB) from fibrinogen. The purpose of this study was to determine whether urokinase has similar activity. Incubation of urokinase with fibrinogen or heparinized plasma results in concentrati...

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Bibliographic Details
Main Authors: Weitz, J I, Leslie, B
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC296708/
https://ncbi.nlm.nih.gov/pubmed/2365816
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