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Urokinase has direct catalytic activity against fibrinogen and renders it less clottable by thrombin.

Recently, we demonstrated that tissue plasminogen activator directly releases fibrinopeptides A and B (FPA and FPB) from fibrinogen. The purpose of this study was to determine whether urokinase has similar activity. Incubation of urokinase with fibrinogen or heparinized plasma results in concentrati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weitz, J I, Leslie, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC296708/
https://ncbi.nlm.nih.gov/pubmed/2365816
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