Establishment and characterisation of a new breast cancer xenograft obtained from a woman carrying a germline BRCA2 mutation

BACKGROUND: The BRCA2 gene is responsible for a high number of hereditary breast and ovarian cancers, and studies of the BRCA2 biological functions are limited by the lack of models that resemble the patient's tumour features. The aim of this study was to establish and characterise a new human...

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Hlavní autoři: de Plater, L, Laugé, A, Guyader, C, Poupon, M-F, Assayag, F, de Cremoux, P, Vincent-Salomon, A, Stoppa-Lyonnet, D, Sigal-Zafrani, B, Fontaine, J-J, Brough, R, Lord, C J, Ashworth, A, Cottu, P, Decaudin, D, Marangoni, E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967069/
https://ncbi.nlm.nih.gov/pubmed/20877358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605900
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