(1)H nuclear magnetic resonance spectroscopy characterisation of metabolic phenotypes in the medulloblastoma of the SMO transgenic mice

BACKGROUND: Human medulloblastomas exhibit diverse molecular pathology. Aberrant hedgehog signalling is found in 20–30% of human medulloblastomas with largely unknown metabolic consequences. METHODS: Transgenic mice over-expressing smoothened (SMO) receptor in granule cell precursors with high incid...

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Detalhes bibliográficos
Main Authors: Hekmatyar, S K, Wilson, M, Jerome, N, Salek, R M, Griffin, J L, Peet, A, Kauppinen, R A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967063/
https://ncbi.nlm.nih.gov/pubmed/20842126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605890
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