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Scavenging Effects of Dexrazoxane on Free Radicals
Dexrazoxane (ICRF-187) has been clinically used to reduce doxorubicin-induced cardiotoxicity for more than 20 years. It has been proposed that dexrazoxane may act through its rings-opened hydrolysis product ADR-925, which can either remove iron from the iron-doxorubicin complex or bind to free iron,...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
the Society for Free Radical Research Japan
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966934/ https://ncbi.nlm.nih.gov/pubmed/21103033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.10-64 |
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