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Glucocorticoid Generates ROS to Induce Oxidative Injury in the Hippocampus, Leading to Impairment of Cognitive Function of Rats

The present study attempted to clarify whether over-secretion of glucocorticoids in the serum caused by increased hypothalamus-pituitary-adrenal activity induces oxidative stress in the rat brain, and how the stress causes the emergence of cognitive deficits. When rats were subcutaneously injected w...

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Autori principali: Sato, Hiroya, Takahashi, Takeyuki, Sumitani, Kazumi, Takatsu, Hirokatsu, Urano, Shiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: the Society for Free Radical Research Japan 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966932/
https://ncbi.nlm.nih.gov/pubmed/21103031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.10-58
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