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The role of fibronectin binding in the rat model of experimental endocarditis caused by Streptococcus sanguis.

Inactivation of fibronectin (Fn) binding by insertional mutagenesis of Streptococcus sanguis with Tn916 reduces virulence of this bacterium in the rat model of infective endocarditis (IE). Transconjugants were screened for Fn adherence using an ELISA adherence test. One transconjugant had a decrease...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Lowrance, J H, Baddour, L M, Simpson, W A
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296682/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164050/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114717
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