Substance P Modulates Colitis-Asscociated Fibrosis

Substance P (SP) and the neurokinin-1 receptor (NK-1R) are involved in the development of colitis and mucosal healing after colonic inflammation. We studied whether SP modulates colonic fibrosis by using a chronic model of trinitrobenzenesulfonic acid (TNBS)-induced colitis in wild-type (WT) and NK-...

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Main Authors: Koon, Hon Wai, Shih, David, Karagiannides, Iordanes, Zhao, Dezheng, Fazelbhoy, Zafeer, Hing, Tressia, Xu, Hua, Lu, Bao, Gerard, Norma, Pothoulakis, Charalabos
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966789/
https://ncbi.nlm.nih.gov/pubmed/20889569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100314
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