Toll-like receptor 9-mediated inhibition of apoptosis occurs through suppression of FoxO3a activity and induction of FLIP expression

Synthetic oligodeoxynucleotides (ODN) with a CpG-motif are recognized by Toll-like receptor 9 (TLR9) and pleiotropic immune responses are elicited. Stimulation of macrophages with TLR9 agonist prevented apoptosis induced by serum deprivation through increased expression of FLICE-like inhibitory prot...

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Autori principali: Lim, Eun-Jung, Park, Dae-Weon, Lee, Jin-Gu, Lee, Chu-Hee, Bae, Yoe-Sik, Hwang, Young-Chul, Jeong, Jae-Weon, Chin, Byung-Rho, Baek, Suk-Hwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Biochemistry and Molecular Biology 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966745/
https://ncbi.nlm.nih.gov/pubmed/20739833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.10.070
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