Involvement of cyclic adenosine monophosphate in the interleukin 4 inhibitory effect on interleukin 2-induced lymphokine-activated killer generation.

In previous studies, IL-4 has been reported to interfere with IL-2-driven generation of lymphokine-activated killer (LAK) activity. In this investigation, we have demonstrated that IL-4 inhibited the IL-2-induced differentiation of large granular lymphocytes (LGL) into LAK effectors by a mechanism i...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Blay, J Y, Branellec, D, Robinet, E, Dugas, B, Gay, F, Chouaïb, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296658/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2161432/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114653
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