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Involvement of cyclic adenosine monophosphate in the interleukin 4 inhibitory effect on interleukin 2-induced lymphokine-activated killer generation.

In previous studies, IL-4 has been reported to interfere with IL-2-driven generation of lymphokine-activated killer (LAK) activity. In this investigation, we have demonstrated that IL-4 inhibited the IL-2-induced differentiation of large granular lymphocytes (LGL) into LAK effectors by a mechanism i...

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Bibliographische Detailangaben
Hauptverfasser: Blay, J Y, Branellec, D, Robinet, E, Dugas, B, Gay, F, Chouaïb, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC296658/
https://ncbi.nlm.nih.gov/pubmed/2161432
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