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Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance.

Obesity is characterized by decreased rates of skeletal muscle insulin-mediated glucose uptake (IMGU). Since IMGU equals the product of the arteriovenous glucose difference (AVGd) across muscle and blood flow into muscle, reduced blood flow and/or tissue activity (AVGd) can lead to decreased IMGU. T...

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Опубликовано в::J Clin Invest
Главные авторы: Laakso, M, Edelman, S V, Brechtel, G, Baron, A D
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1990
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296649/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2189893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114644
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