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Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

Despite the capacity of chaperones and other homeostatic components to restore folding equilibrium, cells appear poorly adapted for chronic oxidative stress that increases in cancer and in metabolic and neurodegenerative diseases. Modulation of endogenous cellular defense mechanisms represents an in...

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Main Authors: Calabrese, Vittorio, Cornelius, Carolin, Dinkova-Kostova, Albena T., Calabrese, Edward J., Mattson, Mark P.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966482/
https://ncbi.nlm.nih.gov/pubmed/20446769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.3074
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