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Mitotic Phosphorylation of Cdc25B Ser(321) Disrupts 14-3-3 Binding to the High Affinity Ser(323) Site
Cdc25B is a key regulator of entry into mitosis, and its activity and localization are regulated by binding of the 14-3-3 dimer. There are three 14-3-3 binding sites on Cdc25B, with Ser(323) being the highest affinity binding and is highly homologous to the Ser(216) 14-3-3 binding site on Cdc25C. Lo...
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| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966050/ https://ncbi.nlm.nih.gov/pubmed/20801879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138412 |
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