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Double Strand Break Unwinding and Resection by the Mycobacterial Helicase-Nuclease AdnAB in the Presence of Single Strand DNA-binding Protein (SSB)

Mycobacterial AdnAB is a heterodimeric DNA helicase-nuclease and 3′ to 5′ DNA translocase implicated in the repair of double strand breaks (DSBs). The AdnA and AdnB subunits are each composed of an N-terminal motor domain and a C-terminal nuclease domain. Inclusion of mycobacterial single strand DNA...

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Detalhes bibliográficos
Main Authors: Unciuleac, Mihaela-Carmen, Shuman, Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966045/
https://ncbi.nlm.nih.gov/pubmed/20736178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162925
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