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Importance of Residue 13 and the C-Terminus for the Structure and Activity of the Antimicrobial Peptide Aurein 2.2

Previous studies on aurein 2.2 and 2.3 in DMPC/DMPG and POPC/POPG membranes have shown that bilayer thickness and phosphatidylglycerol content have a significant impact on the interaction of these peptides with membrane bilayers. Further examination with the DiSC(3)5 assay has indicated that aurein...

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Bibliografiske detaljer
Main Authors: Cheng, John T.J., Hale, John D., Kindrachuk, Jason, Jessen, Havard, Elliott, Melissa, Hancock, Robert E.W., Straus, Suzana K.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965939/
https://ncbi.nlm.nih.gov/pubmed/21044590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.077
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