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Tumour necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation

BACKGROUND: Tumour necrosis reflects the presence of hypoxia, which can be indicative of an aggressive tumour phenotype. The aim of this study was to investigate whether histological necrosis is a useful predictor of outcome in patients with pancreatic ductal carcinoma (PDC). METHODS: We reviewed hi...

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Detalhes bibliográficos
Principais autores: Hiraoka, N, Ino, Y, Sekine, S, Tsuda, H, Shimada, K, Kosuge, T, Zavada, J, Yoshida, M, Yamada, K, Koyama, T, Kanai, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965866/
https://ncbi.nlm.nih.gov/pubmed/20736942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605854
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