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Molecular characterization of a somatically mutated anti-DNA antibody bearing two systemic lupus erythematosus-related idiotypes.

We report the molecular characterization of 2A4, an IgG, DNA-binding antibody bearing the 3I and F4 idiotypes which are associated with anti-DNA antibodies in serum of patients with systemic lupus erythematosus (SLE). The antibody is produced by an EBV-transformed B cell line derived from a patient...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Davidson, A, Manheimer-Lory, A, Aranow, C, Peterson, R, Hannigan, N, Diamond, B
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296585/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2110188/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114584
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