Molecular characterization of a somatically mutated anti-DNA antibody bearing two systemic lupus erythematosus-related idiotypes.

We report the molecular characterization of 2A4, an IgG, DNA-binding antibody bearing the 3I and F4 idiotypes which are associated with anti-DNA antibodies in serum of patients with systemic lupus erythematosus (SLE). The antibody is produced by an EBV-transformed B cell line derived from a patient...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Davidson, A, Manheimer-Lory, A, Aranow, C, Peterson, R, Hannigan, N, Diamond, B
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1990
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296585/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2110188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114584
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