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Efficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain

The Escherichia coli DNA repair enzyme MutY plays an important role in the prevention of DNA mutations by removing misincorporated adenine residues from 7,8-dihydro-8-oxo-2′-deoxyguanosine:2′-deoxyadenosine (OG:A) mispairs. The N-terminal domain of MutY (Stop 225, Met1–Lys225) has a sequence and str...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chmiel, Nikolas H., Golinelli, Marie-Pierre, Francis, Anthony W., David, Sheila S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2001
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC29658/
https://ncbi.nlm.nih.gov/pubmed/11139626
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