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ATORVASTATIN OR TRANSGENIC EXPRESSION OF TFPI INHIBITS COAGULATION INITIATED BY ANTI-NONGAL IgG BINDING TO PORCINE AORTIC ENDOTHELIAL CELLS
BACKGROUND: Intravascular thrombosis remains a hurdle to successful xenotransplantation. Tissue factor (TF) expression on porcine aortic endothelial cells (PAECs), which results from their activation by xenoreactive antibodies (Abs) to Galα1,3Gal (Gal) and subsequent complement activation, plays an...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965779/ https://ncbi.nlm.nih.gov/pubmed/20553382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03950.x |
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