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ATORVASTATIN OR TRANSGENIC EXPRESSION OF TFPI INHIBITS COAGULATION INITIATED BY ANTI-NONGAL IgG BINDING TO PORCINE AORTIC ENDOTHELIAL CELLS

BACKGROUND: Intravascular thrombosis remains a hurdle to successful xenotransplantation. Tissue factor (TF) expression on porcine aortic endothelial cells (PAECs), which results from their activation by xenoreactive antibodies (Abs) to Galα1,3Gal (Gal) and subsequent complement activation, plays an...

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Detalhes bibliográficos
Main Authors: Lin, CC, Ezzelarab, M, Hara, H, Long, C, Lin, CW, Dorling, A, Cooper, DKC
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965779/
https://ncbi.nlm.nih.gov/pubmed/20553382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03950.x
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