Epstein-Barr virus induces aggressive lymphoproliferative disorders of human B cell origin in SCID/hu chimeric mice.

C.B-17 scid mice were reconstituted by intraperitoneal injection of human tonsil cells or PBL from EBV-seronegative donors. Subsequent injection of EBV resulted in the rapid development (within 19-33 d) of aggressive, fatal, lymphoproliferative disorders of human B cell origin. Autopsies revealed so...

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Publié dans:	J Clin Invest
Auteurs principaux:	Cannon, M J, Pisa, P, Fox, R I, Cooper, N R
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296572/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2156900/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114573
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