Diclofenac Hypersensitivity: Antibody Responses to the Parent Drug and Relevant Metabolites

BACKGROUND: Hypersensitivity reactions against nonsteroidal antiinflammatory drugs (NSAIDs) like diclofenac (DF) can manifest as Type I-like allergic reactions including systemic anaphylaxis. However, except for isolated case studies experimental evidence for an IgE-mediated pathomechanism of DF hyp...

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Detalhes bibliográficos
Main Authors: Harrer, Andrea, Lang, Roland, Grims, Robert, Braitsch, Michaela, Hawranek, Thomas, Aberer, Werner, Vogel, Lothar, Schmid, Walther, Ferreira, Fatima, Himly, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965666/
https://ncbi.nlm.nih.gov/pubmed/21060839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013707
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