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Alcohol-Induced Alterations in Hepatic Microtubule Dynamics Can Be Explained by Impaired Histone Deacetylase 6 Function

We have been using polarized, hepatic WIF-B cells to examine ethanol-induced liver injury. These cells polarize in culture and maintain numerous liver-specific activities including the ability to metabolize alcohol. Previously, we found that microtubules were more highly acetylated and more stable i...

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Detalhes bibliográficos
Main Authors: Shepard, Blythe D., Joseph, Rohan A., Kannarkat, George T., Rutledge, Tara M., Tuma, Dean J., Tuma, Pamela L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965519/
https://ncbi.nlm.nih.gov/pubmed/18697214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22481
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