A Large T Cell Invagination with CD2 Enrichment Resets Receptor Engagement in the Immunological Synapse

T cell activation is driven by the TCR and complemented by costimulation. We have studied the dynamics of ligand-engagement of the costimulatory receptor CD2 in T cell/APC couples. Thousands of ligand-engaged CD2 molecules were included in a large T cell invagination at the center of the cellular in...

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Главные авторы: Singleton, Kentner, Parvaze, Nadia, Dama, Kavyya R., Chen, Kenneth S., Jennings, Paula, Purtic, Bozidar, Sjaastad, Michael D., Gilpin, Christopher, Davis, Mark M., Wülfing, Christoph
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965457/
https://ncbi.nlm.nih.gov/pubmed/16982875
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