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Adaptation to bacterial lipopolysaccharide controls lipopolysaccharide-induced tumor necrosis factor production in rabbit macrophages.

These experiments provide an explanation for the observation that two intravenous injections of lipopolysaccharide (LPS) spaced 5 h apart in rabbits cause tumor necrosis factor/cachectin (TNF) levels to rise in the blood only after the first LPS injection. Herein we show that treatment of elicited p...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Mathison, J C, Virca, G D, Wolfson, E, Tobias, P S, Glaser, K, Ulevitch, R J
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296541/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2318968/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114542
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