Epidermal growth factor-stimulated phosphoinositide hydrolysis in cultured rat inner medullary collecting tubule cells. Regulation by G protein, calcium, and protein kinase C.

Epidermal growth factor (EGF) exhibits specific saturable binding to cultured rat inner medullary collecting tubule cells and stimulates inositol trisphosphate (IP3) production by these cells in a dose-dependent fashion. EGF-stimulated IP3 production is enhanced by GTP gamma s or AIF4- and is inhibi...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Teitelbaum, I, Strasheim, A, Berl, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1990
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2156892/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114534
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