Daily genetic profiling indicates JAK/STAT signaling promotes early hepatic stellate cell transdifferentiation

AIM: To identify signaling pathways and genes that initiate and commit hepatic stellate cells (HSCs) to transdifferentiation. METHODS: Primary HSCs were isolated from male Sprague-Dawley rats and cultured on plastic for 0-10 d. Gene expression was assessed daily (quiescent to day 10 culture-activati...

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Main Authors: Lakner, Ashley M, Moore, Cathy C, Gulledge, Alyssa A, Schrum, Laura W
格式: Artigo
語言:Inglês
出版: Baishideng Publishing Group Co., Limited 2010
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965281/
https://ncbi.nlm.nih.gov/pubmed/20976841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i40.5047
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