Efficacy and Safety of Baclofen for Alcohol Dependence: A Randomized, Double-Blind, Placebo-Controlled Trial

BACKGROUND: Recent clinical trials and case-reports indicate that baclofen, a GABA(B) agonist, may have efficacy for alcohol dependence. Baclofen has been shown to enhance abstinence, to reduce drinking quantity, to reduce craving, and to reduce anxiety in alcohol dependent individuals in two placeb...

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Bibliographic Details
Main Authors: Garbutt, James C, Kampov-Polevoy, Alexei B, Gallop, Robert, Kalka-Juhl, Linda, Flannery, Barbara A.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965272/
https://ncbi.nlm.nih.gov/pubmed/20662805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2010.01273.x
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