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Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA

The recent discovery of genomic 5-hydroxymethylcytosine (hmC) and mutations affecting the respective Tet hydroxylases in leukemia raises fundamental questions about this epigenetic modification. We present a sensitive method for fast quantification of genomic hmC based on specific transfer of radiol...

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Detalhes bibliográficos
Main Authors: Szwagierczak, Aleksandra, Bultmann, Sebastian, Schmidt, Christine S., Spada, Fabio, Leonhardt, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965258/
https://ncbi.nlm.nih.gov/pubmed/20685817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq684
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