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Identification of rare alleles and their carriers using compressed se(que)nsing

Identification of rare variants by resequencing is important both for detecting novel variations and for screening individuals for known disease alleles. New technologies enable low-cost resequencing of target regions, although it is still prohibitive to test more than a few individuals. We propose...

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Detalhes bibliográficos
Main Authors: Shental, Noam, Amir, Amnon, Zuk, Or
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965256/
https://ncbi.nlm.nih.gov/pubmed/20699269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq675
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