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Chemically-Conjugated Bone Morphogenetic Protein-2 on Three-Dimensional Polycaprolactone Scaffolds Stimulates Osteogenic Activity in Bone Marrow Stromal Cells

Poly(ε-caprolactone) (PCL) has received considerable attention in bone tissue engineering. However, the lack of osteoinductive ability of PCL limits its application. The aim of this study was to directly attach bone morphogenetic protein-2 (BMP-2) to PCL scaffolds by a crosslinking conjugation metho...

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Autori principali: Zhang, Huina, Migneco, Francesco, Lin, Chia-Ying, Hollister, Scott J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965194/
https://ncbi.nlm.nih.gov/pubmed/20560772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2010.0132
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