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Chemically-Conjugated Bone Morphogenetic Protein-2 on Three-Dimensional Polycaprolactone Scaffolds Stimulates Osteogenic Activity in Bone Marrow Stromal Cells

Poly(ε-caprolactone) (PCL) has received considerable attention in bone tissue engineering. However, the lack of osteoinductive ability of PCL limits its application. The aim of this study was to directly attach bone morphogenetic protein-2 (BMP-2) to PCL scaffolds by a crosslinking conjugation metho...

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Autors principals: Zhang, Huina, Migneco, Francesco, Lin, Chia-Ying, Hollister, Scott J.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965194/
https://ncbi.nlm.nih.gov/pubmed/20560772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2010.0132
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