A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules

Prostate specific membrane antigen (PSMA) is a membrane-bound glutamate carboxypeptidase overexpressed in many forms of prostate cancer. Our laboratory has recently disclosed a class of small molecules, called ARM-Ps (antibody-recruiting molecule targeting prostate cancer) that are capable of enhanc...

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Main Authors: Zhang, Andrew X., Murelli, Ryan P., Barinka, Cyril, Michel, Julien, Cocleaza, Alexandra, Jorgensen, William L., Lubkowski, Jacek, Spiegel, David A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965167/
https://ncbi.nlm.nih.gov/pubmed/20726553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104591m
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